P-nitrobenzyl bromide CAS 100-11-8
| CAS No. | 100-11-8 |
| Molecular Formula | C7H6BrNO2 |
| Molecular Weight | 216.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including P-nitrobenzyl bromide.
P-nitrobenzyl bromide (CAS 100-11-8) is a high-purity analytical reference standard with the molecular formula C7H6BrNO2 and a molecular weight of 216.03 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, P-nitrobenzyl bromide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 216.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures P-nitrobenzyl bromide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6BrNO2 |
| Molecular Weight | 216.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related P Standards
- 2-Nitrobenzyl Bromide (CAS 3958-60-9)
- 4-Nitrobenzyl Carbonochloridate (CAS 4457-32-3)
- 2-Methyl-1-(4-nitrobenzyl)imidazole (CAS 56643-86-8)
- 4-(4-Nitrobenzyl)pyridine (CAS 1083-48-3)
- 2-(4-nitrobenzyl)pyridine (CAS 620-87-1)
- 1-(4-Nitrobenzyl)-1H-pyrazol-4-ol (CAS 1598523-99-9)
- 1-(3-Nitrobenzyl)-1H-pyrazol-4-ol (CAS 1603412-28-7)
- 1-[(4-Nitrobenzyl)oxy]-1H-imidazole (CAS 320424-37-1)
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Why CATO?
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