N,N,N＇,N＇-Tetramethyl-p-phenylenediamine CAS 100-22-1
| CAS No. | 100-22-1 |
| Molecular Formula | C10H16N2 |
| Molecular Weight | 164.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 164.25 g/mol gives N,N,N＇,N＇-Tetramethyl-p-phenylenediamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N,N,N＇,N＇-Tetramethyl-p-phenylenediamine (CAS 100-22-1) is a high-purity analytical reference standard with the molecular formula C10H16N2 and a molecular weight of 164.25 g/mol.
The molecular framework of N,N,N＇,N＇-Tetramethyl-p-phenylenediamine (C10H16N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N,N,N＇,N＇-Tetramethyl-p-phenylenediamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H16N2 |
| Molecular Weight | 164.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Recommended Standards
- Pirfenidone Impurity 35 (CAS 2412-49-9)
- N,N-Diethyl-p-phenylenediamine (CAS 93-05-0)
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