1-[(2-Methyl-4-methylsulfonyl-6-nitro)phenyl]-piperazine CAS 1000018-29-0
| CAS No. | 1000018-29-0 |
| Molecular Formula | C12H17N3O4S |
| Molecular Weight | 299.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[(2-Methyl-4-methylsulfonyl-6-nitro)phenyl]-piperazine (CAS 1000018-29-0) is a high-purity analytical reference standard with the molecular formula C12H17N3O4S and a molecular weight of 299.35 g/mol.
The molecular framework of 1-[(2-Methyl-4-methylsulfonyl-6-nitro)phenyl]-piperazine (C12H17N3O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17N3O4S |
| Molecular Weight | 299.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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Recommended Standards
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- Zopiclone Impurity 3 (CAS CATO-C4X-30713)
- 2-(1-(3-(Trifluoromethyl)phenyl)ethylidene)malononitrile (CAS 866143-71-7)
- 8-Methoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid (CAS 247225-89-4)
- Ethyl 5,5-dimethylocta-2,7-diynoate (CAS 2557181-92-5)
- 2-(Hydroxymethyl)-5-methylcyclohexa-2,5-diene-1,4-dione (CAS 40870-52-8)
- (S)-2-(((S)-1-Ethoxy-3-(4-nitrophenyl)-1-oxopropan-2-yl)amino)propanoic acid (CAS 103451-56-5)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
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