tert-Butyl 3-bromo-5-fluoro-1h-indole-1-carboxylate CAS 1000183-46-9
| CAS No. | 1000183-46-9 |
| Molecular Formula | C13H13BrFNO2 |
| Molecular Weight | 314.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl 3-bromo-5-fluoro-1h-indole-1-carboxylate.
tert-Butyl 3-bromo-5-fluoro-1h-indole-1-carboxylate (CAS 1000183-46-9) is a high-purity analytical reference standard with the molecular formula C13H13BrFNO2 and a molecular weight of 314.15 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, tert-Butyl 3-bromo-5-fluoro-1h-indole-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 314.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures tert-Butyl 3-bromo-5-fluoro-1h-indole-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13BrFNO2 |
| Molecular Weight | 314.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-butyl N-(7-bromoimidazo[2,1-f][1,2,4]triazin-4-yl)carbamate (CAS 2328091-02-5)
- (3-(1-Phenyl-1H-benzo[d]imidazol-2-yl)phenyl)boronic acid (CAS 1214723-26-8)
- Ethyl 2-(6,8-dichloro-2-methyl-4-oxoquinazolin-3(4H)-yl)acetate (CAS 55469-83-5)
- 4-Bromo-2-mercapto-6-(trifluoromethyl)benzothiazole (CAS 1215205-88-1)
- 2-(3,3,3-Trifluoropropyl)-1,3-dioxolane (CAS 773102-97-9)
- 5-Amino-4-methoxypyridin-2-ol (CAS 1309379-09-6)
- 1,5-Dihydroxy-2,6-diisobutylanthracene-9,10-dione (CAS 76643-53-3)
- 4-(Difluoromethyl)-3,5-diiodopyridin-2-ol (CAS 1805046-55-2)
- Formoterol Impurity 28 (CAS 201677-59-0)
- Methyl(2-methyl-1,3-dioxoisoindolin-4-yl)carbamic chloride (CAS 71173-81-4)
- L-Ascorbic acid 2-(dihydrogen phosphate) cyclohexanamine- (CAS 82134-96-1)
- 2,5-Dichloro-N-((1-hydroxycyclopentyl)methyl)benzamide (CAS 1219903-59-9)
- Methyl 3-Oxohexadecanoate (CAS 14427-53-3)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com