1-tert-Butyl 2-methyl 4,4-difluoropyrrolidine-1,2-dicarboxylate CAS 1000313-00-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1000313-00-7
Molecular FormulaC11H17F2NO4
Molecular Weight265.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-tert-Butyl 2-methyl 4,4-difluoropyrrolidine-1,2-dicarboxylate CAS 1000313-00-7 chemical structure

Description

The occurrence of 1-tert-Butyl 2-methyl 4,4-difluoropyrrolidine-1,2-dicarboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1-tert-Butyl 2-methyl 4,4-difluoropyrrolidine-1,2-dicarboxylate (CAS 1000313-00-7), a certified reference material (molecular formula C11H17F2NO4, MW 265.25 g/mol) for analytical method development and quality control.

The molecular framework of 1-tert-Butyl 2-methyl 4,4-difluoropyrrolidine-1,2-dicarboxylate (C11H17F2NO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H17F2NO4
Molecular Weight265.25 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms1

Recommended Standards

Why CATO?