3-[(6-Chloro-[1,3]dioxolo[4,5-g]quinolin-7-ylmethyl)-amino]-propan-1-ol CAS 1000348-12-8
| CAS No. | 1000348-12-8 |
| Molecular Formula | C14H15ClN2O3 |
| Molecular Weight | 294.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-[(6-Chloro-[1,3]dioxolo[4,5-g]quinolin-7-ylmethyl)-amino]-propan-1-ol.
3-[(6-Chloro-[1,3]dioxolo[4,5-g]quinolin-7-ylmethyl)-amino]-propan-1-ol (CAS 1000348-12-8), molecular formula C14H15ClN2O3 and molecular weight 294.73 g/mol, is a CATO reference standard with documented purity and traceability.
3-[(6-Chloro-[1,3]dioxolo[4,5-g]quinolin-7-ylmethyl)-amino]-propan-1-ol (C14H15ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-[(6-Chloro-[1,3]dioxolo[4,5-g]quinolin-7-ylmethyl)-amino]-propan-1-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15ClN2O3 |
| Molecular Weight | 294.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
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- N,N-Dimethyl-N′-[[1-(4-methylphenyl)-5-oxo-3-pyrrolidinyl]methyl]sulfamide (CAS 954608-61-8)
- 1-(2-Methylpyrazolo[1,5-a]pyrazin-4-yl)piperidin-4-amine (CAS 1707372-39-1)
- 7-fluoroquinolin-8-ol (CAS 35048-10-3)
- 4-Chloro-6-methoxyquinazolin-7-yl acetate (CAS 179688-03-0)
- tert-Butyl 3-(hydroxymethyl)piperidine-1-carboxylate (CAS 116574-71-1)
- BDD26-2Th26Br (CAS 1439937-07-1)
- 3-Aminothieno[3,2-b]pyridine-2-carboxylic acid (CAS 1203257-15-1)
- 5-Bromo-6-(2,2,2-trifluoroethoxy)-pyridin-3-ylamine (CAS 1372606-85-3)
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