1,3-Dihydrospiro[indene-2,2'-pyrrolidine]-5,6-diol CAS 100038-08-2
| CAS No. | 100038-08-2 |
| Molecular Formula | C12H15NO2 |
| Molecular Weight | 205.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,3-Dihydrospiro[indene-2,2'-pyrrolidine]-5,6-diol (CAS 100038-08-2), molecular formula C12H15NO2 and molecular weight 205.25 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1,3-Dihydrospiro[indene-2,2'-pyrrolidine]-5,6-diol (C12H15NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 205.25 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,3-Dihydrospiro[indene-2,2'-pyrrolidine]-5,6-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15NO2 |
| Molecular Weight | 205.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Dihydrospiro Standards
- 2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-4,5-diol (CAS 100038-00-4)
- 2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-5,6-diol (CAS 100038-04-8)
- 5'-Methyl-1',2'-dihydrospiro[1,3-dioxolane-2,3'-indole]-2'-one (CAS 75822-58-1)
- 2'-Ethyl-5',6'-dihydrospiro[piperidine-4,4'-pyrrolo[1,2-b]pyrazole] (CAS 1026988-58-8)
- 3',4'-Dihydrospiro[piperidine-4,2'-pyrano[3,2-c]pyridine] (CAS 1824281-31-3)
- (2,3-Dihydrospiro[indene-1,2'-[1,3]dioxolan]-5-yl)methanol (CAS 760995-52-6)
- (2,3-Dihydrospiro[indene-1,2'-[1,3]dioxolan]-6-yl)methanol (CAS 866849-00-5)
- Methyl 1,3-dihydrospiro[indene-2,2'-oxirane]-3'-carboxylate (CAS 1484522-90-8)
Recommended Standards
- 2-Phenyl-2-(pyrrolidin-1-yl)acetic acid (CAS 100390-48-5)
- N-Cyclopropyl-3-methoxy-4-methylbenzamide (CAS 1007767-11-4)
- 1,2,4-Triazolo[3,4-b]benzothiazole-5-methanol (CAS 69243-49-8)
- (R)-2-phenyl-2-(pyrrolidin-1-yl)acetic acid (CAS 1007877-77-1)
- 5-Oxo-2-phenyl-1-(tetrahydro-2-furanylmethyl)-3-pyrrolidinecarboxylic acid (CAS 1290720-65-8)
- 2H-Benzimidazol-2-one (CAS 43135-91-7)
- Tert-butyl (R)-3-(4-amino-3-iodo-1H-pyrazolo[4,3-c]pyridin-1-yl)piperidine-1-carboxylate (CAS 2056025-28-4)
- (S)-2-Amino-3-(thiophen-2-yl)propanoic acid hydrochloride (CAS 123053-24-7)
- Methyl (R)-11b-methyl-6-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indole-7-carboxylate (CAS 1446261-55-7)
- Afoxolaner Impurity 33 (CAS CATO-C4X-313733)
- 4-(2,5-DIoxo-pyrrolidin-1-yloxysulfonyl)-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester (CAS 1807503-84-9)
- Remdesivir Impurity 25 (CAS 1256490-31-9)
- 1-(4-Methoxyphenethyl)azetidin-3-ol (CAS 1271553-42-4)
- Antiarrhythmic peptide (cattle atrium) (CAS 81771-37-1)
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