4-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-6-ol CAS 100047-41-4
| CAS No. | 100047-41-4 |
| Molecular Formula | C6H6N4OS |
| Molecular Weight | 182.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-6-ol (C6H6N4OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-6-ol (CAS 100047-41-4) is a high-purity analytical reference standard with the molecular formula C6H6N4OS and a molecular weight of 182.20 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-6-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6N4OS |
| Molecular Weight | 182.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- 2-(Methylthio)-9H-purin-6-ol (CAS 5446-89-9)
- 2-(Methylthio)Pyrazolo[1,5-A][1,3,5]Triazin-4(3H)-One (CAS 54346-18-8)
- 3-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 90914-36-6)
- 7-(Methylthio)-5,6-dihydro-4H-imidazo[4,5-d]pyridazin-4-one (CAS 3438-77-5)
- 2-(Methylthio)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine (CAS 1011408-19-7)
- 5-(Methylthio)-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine (CAS 93886-72-7)
- 2-Methyl-3-(methylthio)benzoic acid (CAS 1149384-42-8)
- 2-Methyl-4-(methylthio)benzoic acid (CAS 118939-08-5)
Recommended Standards
- Apalutamide Impurity 21 (CAS CATO-C4X-274921)
- 6-methylsulfanyl-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one (CAS 100047-42-5)
- Hydantoin Impurity 4 (CAS 2361-15-1)
- 3-Hydroxy-2-methyl-2H-pyrazolo[4,3-d]pyrimidine-7(4H)-thione (CAS 100565-58-0)
- 3-(4-(Benzyloxy)phenyl)prop-2-yn-1-ol (CAS 518038-90-9)
- 2-(2-Isocyanoethoxy)-2-methylpropane (CAS 1313807-04-3)
- 3,5-Di-O-acetyl-2-deoxyadenosine (CAS 106568-79-0)
- (S)-Methyl 3-([1,1'-biphenyl]-4-yl)-2-aminopropanoate (CAS 139040-51-0)
- 3-(3-(4-Acetylphenyl)ureido)propanoic acid (CAS 1017667-78-5)
- 1,7-Dibromo-heptan-4-one (CAS 89774-18-5)
- 3-(Aminomethyl)benzaldehyde (CAS 219919-14-9)
- Benzo[d]imidazo[2,1-b]thiazole-2-carbaldehyde (CAS 114095-04-4)
- 6-Amino-2-(propylthio)pyrimidin-4-ol (CAS 2917-02-4)
- T-Peptide (CAS 2022956-62-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com