2-(2,4-Dichloropyrimidin-5-yl)acetonitrile CAS 1000548-88-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1000548-88-8
Molecular FormulaC6H3Cl2N3
Molecular Weight188.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2,4-Dichloropyrimidin-5-yl)acetonitrile CAS 1000548-88-8 chemical structure

Description

The occurrence of 2-(2,4-Dichloropyrimidin-5-yl)acetonitrile is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(2,4-Dichloropyrimidin-5-yl)acetonitrile (CAS 1000548-88-8), molecular formula C6H3Cl2N3 and molecular weight 188.01 g/mol, is a CATO reference standard with documented purity and traceability.

2-(2,4-Dichloropyrimidin-5-yl)acetonitrile (C6H3Cl2N3) contains a nitrile group, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H3Cl2N3
Molecular Weight188.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentCl-containing
Nitrogen Atoms3

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