1-Bromo-4-chloro-2,3-difluorobenzene CAS 1000574-47-9
| CAS No. | 1000574-47-9 |
| Molecular Formula | C6H2BrClF2 |
| Molecular Weight | 227.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-Bromo-4-chloro-2,3-difluorobenzene (CAS 1000574-47-9), molecular formula C6H2BrClF2 and molecular weight 227.43 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-Bromo-4-chloro-2,3-difluorobenzene (C6H2BrClF2) contains fluorine/chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 227.43 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H2BrClF2 |
| Molecular Weight | 227.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 2-Bromo-1-chloro-3,5-difluorobenzene (CAS 1020198-58-6)
- 5-Bromo-1-chloro-2,3-difluorobenzene (CAS 1060813-07-1)
- 1-Bromo-5-chloro-2,3-difluorobenzene (CAS 1160573-26-1)
- 1-Bromo-3-chloro-2,5-difluorobenzene (CAS 1160573-67-0)
- 1-Bromo-2-chloro-3,4-difluorobenzene (CAS 1160574-70-8)
- 2-Bromo-1-chloro-3,4-difluorobenzene (CAS 1208077-25-1)
- 2-Bromo-3-chloro-1,4-difluorobenzene (CAS 1208077-34-2)
- 1-Bromo-4-chloro-2,5-difluorobenzene (CAS 172921-33-4)
Recommended Standards
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- (1R,3r,5S,6r)-3-((tert-Butyldimethylsilyl)oxy)bicyclo[3.1.0]hexan-6-amine (CAS 2139228-56-9)
- Ethyl 6-chloro-4-(trifluoromethyl)picolinate (CAS 939047-74-2)
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- 7-Chloro-4-(4-methylbenzenesulfonyl)-3,4-dihydro-2H-1,4-benzothiazine (CAS 338777-99-4)
- 7-Chloro-3-(3-fluorophenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1707571-78-5)
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- Peptide Impurity 64 (CAS CATO-CPTD788964)
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