2-Bromo-4-(difluoromethoxy)phenylisothiocyanate CAS 1000574-84-4
| CAS No. | 1000574-84-4 |
| Molecular Formula | C8H4BrF2NOS |
| Molecular Weight | 280.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 280.09 g/mol gives 2-Bromo-4-(difluoromethoxy)phenylisothiocyanate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Bromo-4-(difluoromethoxy)phenylisothiocyanate (CAS 1000574-84-4), molecular formula C8H4BrF2NOS and molecular weight 280.09 g/mol, is a CATO reference standard with documented purity and traceability.
2-Bromo-4-(difluoromethoxy)phenylisothiocyanate (C8H4BrF2NOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4BrF2NOS |
| Molecular Weight | 280.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2-(difluoromethoxy)phenylisothiocyanate (CAS 1000575-37-0)
- (3-Bromo-2-fluorophenyl)(pyridin-2-yl)methanone (CAS 1261454-76-5)
- 2-Bromo-7-(difluoromethoxy)benzo[d]thiazole (CAS 1261471-82-2)
- 2-Bromo-4-(difluoromethoxy)benzo[d]thiazole (CAS 1261598-02-0)
- 2-Bromo-3-(4-fluorobenzoyl)pyridine (CAS 2034155-37-6)
- (R)-2-(3-bromo-2,4,5-trifluorophenyl)pyrrolidine (CAS 1241682-47-2)
- (R)-2-(4-bromo-2,3,6-trifluorophenyl)pyrrolidine (CAS 1241682-50-7)
- 5-Bromo-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 1356111-42-6)
Recommended Standards
- Enoxacin Impurity 2 (CAS CATO-C4X-19652)
- Methyl 6-bromo-3-cyano-1H-indazole-4-carboxylate (CAS 885518-67-2)
- 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 1049730-42-8)
- Ethyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxopropanoate (CAS 96568-04-6)
- Methyl 2-(4-ethylphenyl)-2-methylpropanoate (CAS 698394-59-1)
- 2-Chloro-6-fluoroquinoline-4-carboxylic acid (CAS 436096-52-5)
- 3-Bromo-7-ethyl-5-methylpyrazolo[1,5-a]pyrimidine (CAS 43024-40-4)
- 1-(Pyrimidin-5-yl)pyrrolidin-3-amine dihydrochloride (CAS 2227205-15-2)
- 1-Cyclopropyl-N-methylpropan-1-amine (CAS 1179261-46-1)
- Boc-Leu-psi(CH2NH)Leu-OH (A-1880.0250) (CAS 127370-77-8)
- H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Asn-OH (M-1120.0001) (CAS 104180-23-6)
- 3-Methoxy-4-(2,2,2-trifluoroethoxy)benzaldehyde (CAS 76579-47-0)
- Phthalate-Mix 8(CPSIA) (CAS CATO-MPAE111808-ME)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com