5,7-Dichloro-N-(4-chlorobenzyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide CAS 1000575-67-6
| CAS No. | 1000575-67-6 |
| Molecular Formula | C12H7Cl3N4O2S2 |
| Molecular Weight | 409.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 5,7-Dichloro-N-(4-chlorobenzyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 409.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5,7-Dichloro-N-(4-chlorobenzyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000575-67-6) is a high-purity analytical reference standard with the molecular formula C12H7Cl3N4O2S2 and a molecular weight of 409.70 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7Cl3N4O2S2 |
| Molecular Weight | 409.70 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Dichloro Standards
- 5,7-Dichloro-N-(3-chlorophenyl)-N-methylthiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000576-45-3)
- 4,4''-Dichloro-5'-(4-chlorophenyl)-1,1':3',1''-terphenyl (CAS 6326-61-0)
- 7,9-Dichloro-2-phenyl-5-(p-tolyl)-5,10b-dihydro-1H-benzo[e]pyrazolo[1,5-c][1,3]oxazine (CAS 302904-05-8)
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- N-(2-(2,4-Dichloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)methanesulfonamide (CAS 2096338-42-8)
- 4,6-dichloro-2-(methylthio)-5-[({[3-(trifluoromethyl)benzoyl]oxy}imino)methyl]pyrimidine (CAS 680217-29-2)
- 3,4-Dichloro-N-(2,4-dichloro-5-(2-methoxyethoxy)phenyl)benzamide (CAS 338961-30-1)
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Recommended Standards
- 4-((5-Bromo-2-hydroxybenzylidene)amino)-3-(3-chlorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-81-8)
- 4-((5-Bromo-2-hydroxybenzylidene)amino)-3-(2-chlorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-02-3)
- 4-beta-Hydroxy Cholesterol-D7 (CAS 1246302-80-6)
- 2-Bromo-4-(2-chlorophenyl)-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-9-methanol (CAS 62551-41-1)
- 3-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)propanenitrile (CAS 27430-50-8)
- tert-butyl 4-(3-iodo-1-bicyclo[1.1.1]pentanyl)piperidine-1-carboxylate (CAS 2020069-99-0)
- 2-Iodo-5-nitro-1H-indole (CAS 1936633-79-2)
- 898768-40-6 1-(3,5-Dimethylphenyl)-3-(4-fluorophenyl)propan-1-one DTXSID40644583 (CAS 898768-40-6)
- 2-Methyl-1-(7-methylbenzofuran-2-yl)propan-1-amine (CAS 1484251-23-1)
- 2-Cyclopropyl-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid (CAS 1185428-39-0)
- 1-(3-Amino-5-chloropyridin-2-yl)ethan-1-one (CAS 1260671-67-7)
- N,N-Dimethyl-1,2,3,4-tetrahydroisoquinolin-7-amine (CAS 138276-84-3)
- N4-(2-Bromophenyl)-N2-isobutyl-L-asparagine (CAS 1048001-11-1)
- Experimental Allergic Encephalitogenic Peptide (CAS 29705-92-8)
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