2-Bromo-4-chloro-6-fluorophenylisothiocyanate CAS 1000577-50-3
| CAS No. | 1000577-50-3 |
| Molecular Formula | C7H2BrClFNS |
| Molecular Weight | 266.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-4-chloro-6-fluorophenylisothiocyanate.
CATO supplies 2-Bromo-4-chloro-6-fluorophenylisothiocyanate (CAS 1000577-50-3), a certified reference material (molecular formula C7H2BrClFNS, MW 266.52 g/mol) for analytical method development and quality control.
2-Bromo-4-chloro-6-fluorophenylisothiocyanate (C7H2BrClFNS) contains a nitrile group, sulfur-containing functionality, fluorine/chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Bromo-4-chloro-6-fluorophenylisothiocyanate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H2BrClFNS |
| Molecular Weight | 266.52 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2-chloro-5-fluorophenyl isothiocyanate (CAS 1000572-68-8)
- 4-Bromo-2-chloro-6-fluorophenylisothiocyanate (CAS 1000572-98-4)
- 4-Bromo-5-chloro-2-fluorophenyl isothiocyanate (CAS 1000573-33-0)
- 2-Bromo-6-chloro-4-fluorophenyl isothiocyanate (CAS 1000577-54-7)
- 2-Bromo-6-chloro-4-fluorobenzothiazole (CAS 1188042-90-1)
- 4-Bromo-5-chloro-N-isopropylfuran-2-carboxamide (CAS 1427015-29-9)
- 6-Bromo-2-chloro-5-fluorobenzothiazole (CAS 1812890-12-2)
- 5-Bromo-2-chloro-3-(2-methoxyethoxy)pyridine (CAS 1887246-43-6)
Recommended Standards
- 1,5-Dibromo-2-chloro-4-fluorobenzene (CAS 1000578-11-9)
- 1-Nonadecene (CAS 18435-45-5)
- (s)-2-(1-Amino-2-hydroxyethyl)-6-bromo-4-chlorophenol (CAS 1213032-67-7)
- Vortioxetine Impurity 135 (CAS CATO-C4X-1056135)
- (E)-3-(2-chlorophenyl)-2-phenylacrylic acid (CAS 728-50-7)
- 5-(2-Chlorophenyl)-1,2,4-oxadiazol-3-amine (CAS 1342677-58-0)
- 1-(3,5-Dichlorophenyl)-N,5-dimethyl-1H-1,2,4-triazole-3-carboxamide (CAS 338408-39-2)
- 4-(4-(4-Bromophenyl)-5-((naphthalen-1-ylmethyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 676643-89-3)
- Methyl 2-(chloromethyl)-6-(trifluoromethyl)isonicotinate (CAS 1393560-74-1)
- 2-(Chloromethyl)-5-(5-methylfuran-2-yl)-1,3,4-oxadiazole (CAS 876620-46-1)
- 2-Amino-N-isopropyl-N-(3-methoxy-benzyl)-acetamide (CAS 1181707-26-5)
- (±)-Atomoxetine-d5 HCl (phenyl-d5) (CAS 1398065-95-6)
- (4-Bromophenyl)(7-methoxybenzofuran-2-yl)methanone (CAS 477848-09-2)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com