2-Amino-3-bromo-6-fluoro-5-iodobenzonitrile CAS 1000577-79-6
| CAS No. | 1000577-79-6 |
| Molecular Formula | C7H3BrFIN2 |
| Molecular Weight | 340.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-3-bromo-6-fluoro-5-iodobenzonitrile.
2-Amino-3-bromo-6-fluoro-5-iodobenzonitrile (CAS 1000577-79-6), molecular formula C7H3BrFIN2 and molecular weight 340.92 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Amino-3-bromo-6-fluoro-5-iodobenzonitrile (C7H3BrFIN2) is characterized by a nitrile group, fluorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3BrFIN2 |
| Molecular Weight | 340.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br/I-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-5-bromo-6-fluoro-3-iodobenzonitrile (CAS 1000577-88-7)
- Methyl 2-amino-4-(1,1-difluoroethyl)-5-iodobenzoate (CAS 912575-29-2)
- N-(5-amino-2-methoxyphenyl)-2-(2,4-dichlorophenoxy)acetamide (CAS 1020054-37-8)
- Ethyl 3-amino-1H-1,2,4-triazole-1-carboxylate (CAS 41995-94-2)
- N-[2-Amino-4-(4-bromophenyl)-1H-imidazol-1-yl]-N-[(E)-phenylmethylidene]amine (CAS 275358-95-7)
- 5-Amino-N-(4-bromophenyl)-2-methylbenzene-1-sulfonamide (CAS 114500-28-6)
- 3-Amino-N-(2-bromo-5-methylphenyl)benzene-1-sulfonamide (CAS 380569-63-1)
- 4-Amino-N-(4-bromophenyl)-2-methylbenzene-1-sulfonamide (CAS 568554-47-2)
Recommended Standards
- 7-Bromo-4-fluoro-3-iodo-1H-indazole (CAS 1000342-12-0)
- 4,6-Dibromo-3-hydroxy-2-nitrobenzoic acid (CAS 160911-18-2)
- 5-Bromo-4-fluoro-3-iodo-1H-indazole (CAS 1082041-88-0)
- Hydroxychloroquine D5 (CAS 118-42-3(Unlabelled))
- 1-(2-Fluorophenyl)-1H-pyrrole-2-carbaldehyde (CAS 132407-65-9)
- 2-(3-FLUOROPHENOXY)-2-METHYLPROPANOIC ACID (CAS 605680-36-2)
- 5-bromo-3-methyl-1,2-thiazole-4-carbonitrile (CAS 1803561-46-7)
- Methyl 2-(4-bromo-6-fluoropyridin-2-yl)acetate (CAS 1805248-98-9)
- (2-Bromoethylidene)cyclohexane (CAS 932-86-5)
- 5-Bromo-4-nitrobenzo[c][1,2,5]selenadiazole (CAS 1753-20-4)
- 22560-21-0 Potassium hydrotriethylborate Potassium triethylborohydride solution Potassium triethylhydridoborate (CAS 22560-21-0)
- 2-((5-Chloroquinolin-8-yl)oxy)-N-(2-propoxyacetoxy)acetimidamide (CAS 88758-63-8)
- 5-Bromo-1-cyclopentyl-1H-pyrazole (CAS 1368151-58-9)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com