(R)-5-Fluoro-N-(1-(4-isopropoxybenzyl)pyrrolidin-3-yl)-2-methylbenzenesulfonamide CAS 1000592-49-3
| CAS No. | 1000592-49-3 |
| Molecular Formula | C21H27FN2O3S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (R)-5-Fluoro-N-(1-(4-isopropoxybenzyl)pyrrolidin-3-yl)-2-methylbenzenesulfonamide (CAS 1000592-49-3), a certified reference material (molecular formula C21H27FN2O3SHCl, MW 442.97 g/mol) for analytical method development and quality control.
The molecular framework of (R)-5-Fluoro-N-(1-(4-isopropoxybenzyl)pyrrolidin-3-yl)-2-methylbenzenesulfonamide (C21H27FN2O3SHCl) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H27FN2O3S HCl |
| Molecular Weight | 442.97 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related R Standards
- 4-[(2-Fluoro-4-nitrophenoxy)methyl]-1-methylpiperidine (CAS 1000052-54-9)
- 3-Fluoro-4-((1-methylpiperidin-4-yl)methoxy)aniline (CAS 1000053-56-4)
- 2-Fluoro-5-iodo-4-methoxybenzoic acid (CAS 1000162-78-6)
- Ethyl 4-fluoro-3-ethoxybenzoate (CAS 1000207-63-5)
- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
- 2-Fluoro-3-hydroxybenzonitrile (CAS 1000339-24-1)
- 1-(5-Fluoro-2-methylphenyl)pyrrolidine (CAS 1000339-32-1)
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- 4-Aminocyclohexane-1-carbonitrile (CAS 23083-48-9)
- (S)-Propafenone (CAS 107381-32-8)
- [(3-Fluorophenyl)methyl](propyl)amine hydrochloride (CAS 90389-42-7)
- 2-[(Diethylamino)methyl]-4-fluoroaniline (CAS 1153395-75-5)
- (6-(1,10-Phenanthrolin-3-yl)naphthalen-2-yl)diphenylphosphine oxide (CAS 1480371-38-7)
- N,N'-Dimethylpiperazine (CAS 106-58-1)
- HMBR (CAS 1287651-36-8)
- 2-Methoxy-4-phenylpyridine (CAS 53698-46-7)
- Potassium 2-(2-amino-5-iodophenyl)-2-oxoacetate (CAS 287393-80-0)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
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