1-((Tetrahydro-2H-pyran-2-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole CAS 1000802-49-2
| CAS No. | 1000802-49-2 |
| Molecular Formula | C15H25BN2O3 |
| Molecular Weight | 292.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-((Tetrahydro-2H-pyran-2-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1000802-49-2), a certified reference material (molecular formula C15H25BN2O3, MW 292.18 g/mol) for analytical method development and quality control.
The molecular framework of 1-((Tetrahydro-2H-pyran-2-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (C15H25BN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H25BN2O3 |
| Molecular Weight | 292.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Tetrahydro Standards
- (4-Methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)boronic acid (CAS 1141878-27-4)
- 1-((Tetrahydro-2H-pyran-3-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1430751-20-4)
- 3-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-boronic Acid Pinacol Ester (CAS 1853186-01-2)
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- 2-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-2H-indazole-3-carboxylic acid (CAS 1197238-45-1)
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- n-((6,7,8,9-Tetrahydro-5h-[1,2,4]triazolo[4,3-a]azepin-3-yl)methyl)naphthalen-2-amine (CAS 326021-83-4)
Recommended Standards
- tert-Butyl 2-(2-bromoacetyl)pyrrolidine-1-carboxylate (CAS 96551-92-7)
- 3,5-Bis(methoxymethyl)phenylboronic Acid Pinacol Ester (CAS 1003323-26-9)
- Quinazoline, 6-bromo-4-(1-piperidinyl)- (CAS 452348-63-9)
- 2-(3,4-Diethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1005009-95-9)
- Tert-butyl (2-azabicyclo[2.2.2]Octan-6-yl)carbamate hydrochloride (CAS 2031260-93-0)
- N-cyclohexylpiperidine-3-carboxamide (CAS 937778-23-9)
- 1-[2-(1-Piperidyl)ethyl]-1H-pyrazole-4-boronic Acid Pinacol Ester (CAS 1000802-51-6)
- 2-Hydroxy-n-(2,4,6-trimethylphenyl)acetamide (CAS 867299-50-1)
- Ethyl 3-chloro-5-ethoxy-4-((2-methylbenzyl)oxy)benzoate (CAS 1706457-95-5)
- Methyl 4-benzyl-3-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine-7-carboxylate (CAS 1708263-62-0)
- 4-Bromo-2-methyl-5-((piperidin-2-ylmethyl)amino)pyridazin-3(2H)-one (CAS 1714537-37-7)
- (2-Butyl-5-nitrobenzofuran-3-yl)(4-(3-(dibutylamino)-propoxy)phenyl)methanone hydrochloride (CAS 437651-47-3)
- FMOC-(R)-3-AMINO-5-HEXENOIC ACID (CAS 269726-95-6)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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