(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone CAS 1001264-89-6
| CAS No. | 1001264-89-6 |
| Molecular Formula | C24H32ClN5O2 |
| Molecular Weight | 458.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone.
(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone (CAS 1001264-89-6), molecular formula C24H32ClN5O2 and molecular weight 458.00 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone (C24H32ClN5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H32ClN5O2 |
| Molecular Weight | 458.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related S Standards
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- 1-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl)-4-(2-fluorophenyl)piperazine (CAS 477869-37-7)
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- N'-(1-((4-chlorophenyl)sulfonyl)piperidine-4-carbonyl)benzenesulfonohydrazide (CAS 477872-89-2)
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Recommended Standards
- Montelukast Impurity 49 (CAS CATO-C4X-103149)
- Boron Tris(trifluoromethanesulfonate) (CAS 64371-01-3)
- Montelukast Impurity 47 (CAS 1079753-36-8)
- 3-(4-Chlorobenzenesulfonyl)-2-(cyclohexylsulfanyl)-4-methyl-6-phenylpyridine (CAS 339103-35-4)
- 4,6-Dimethoxy-2-(piperazin-1-yl)pyrimidine (CAS 106615-46-7)
- 2-(4-Carboxyphenyl)-1H-benzo[d]imidazole-6-carboxylic acid (CAS 35532-08-2)
- Methyl 5-ethyl-1,6-dioxaspiro[2.5]octane-2-carboxylate (CAS 1561604-24-7)
- 1-(5-Chloro-2-hydroxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 870614-04-3)
- 2-{[3-(2,4-Dichlorophenoxy)propyl]amino}ethanol (CAS 418775-76-5)
- 1-(6-Fluoropyridin-2-yl)ethanone (CAS 501009-05-8)
- N-Acetyl-S-(phenyl-13C6)-L-cysteine (CAS CATO-CCAD302126)
- Arbidol Impurity 52 (CAS CATO-C4X-112952)
- Daprodustat impurity 1 (CAS 2883118-63-4)
- Hexapeptide-9 (CAS 1228371-11-6)
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