1-Methyl-4-(thiophen-2-yl)piperidin-4-ol CAS 100131-91-7
| CAS No. | 100131-91-7 |
| Molecular Formula | C10H15NOS |
| Molecular Weight | 197.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methyl-4-(thiophen-2-yl)piperidin-4-ol.
1-Methyl-4-(thiophen-2-yl)piperidin-4-ol (CAS 100131-91-7) is a high-purity analytical reference standard with the molecular formula C10H15NOS and a molecular weight of 197.30 g/mol.
The molecular framework of 1-Methyl-4-(thiophen-2-yl)piperidin-4-ol (C10H15NOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Methyl-4-(thiophen-2-yl)piperidin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15NOS |
| Molecular Weight | 197.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- N-(thiophen-2-ylmethyl)tetrahydro-2H-pyran-4-amine (CAS 1154883-95-0)
- (1-(Thiophen-3-ylmethyl)pyrrolidin-2-yl)methanol (CAS 1249475-22-6)
- 3-(2-(Thiophen-3-yl)ethoxy)pyrrolidine (CAS 1339594-34-1)
- (4-(Thiophen-3-yl)tetrahydro-2H-pyran-4-yl)methanamine (CAS 1447965-82-3)
- 4-(Thiophen-2-ylmethyl)piperidin-4-ol (CAS 1521019-01-1)
- (1-(Thiophen-2-ylmethyl)pyrrolidin-3-yl)methanol (CAS 170749-89-0)
- (4-(Thiophen-2-yl)tetrahydro-2H-pyran-4-yl)methanamine (CAS 906422-74-0)
- 1-(Thiophen-3-ylmethyl)piperidin-4-ol (CAS 864388-84-1)
Recommended Standards
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- 5-fluoro-2,3-dihydrospiro[indene-1,2'-pyrrolidine] (CAS 1211594-23-8)
- N-(4-methyl-1,3-thiazol-2-yl)piperidin-4-amine (CAS 1017046-71-7)
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- (2-cyclopropylcyclohexyl)methanamine hydrochloride (CAS 1909337-77-4)
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- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
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