N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxypropanamide CAS 100144-13-6
| CAS No. | 100144-13-6 |
| Molecular Formula | C9H14N4O4 |
| Molecular Weight | 242.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxypropanamide (CAS 100144-13-6) is a high-purity analytical reference standard with the molecular formula C9H14N4O4 and a molecular weight of 242.23 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxypropanamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H14N4O4 |
| Molecular Weight | 242.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 4 |
Related N Standards
- 4-Amino-1-((2R,4S,5R)-4-(aminooxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 103251-39-4)
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- Methyl 2-(5-Amino-4-cyano-2-furyl)benzoate (CAS 1261268-76-1)
- Methyl 4-(5-Amino-4-cyano-2-furyl)benzoate (CAS 1261268-86-3)
- Methyl 3-(5-Amino-4-cyano-2-furyl)benzoate (CAS 1261269-02-6)
- 2-Amino-5-(4-formylphenyl)nicotinic acid (CAS 1261953-83-6)
- (S)-2-Amino-3-(((S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl)amino)propanoic acid (CAS 88452-76-0)
- 2-Amino-2-deoxycytidine (CAS 26889-42-9)
Recommended Standards
- [2,2'-Bipyridine]-4,4'-dicarboxamide (CAS 100137-02-8)
- methyl 6-oxo-5H,6H-pyrrolo[1,2-a]quinoxaline-3-carboxylate (CAS 1006385-87-0)
- Pantoprazole Impurity 68 (CAS CATO-C4X-139968)
- Diethyl 4,5-dioxocyclopentane-1,3-dicarboxylate (CAS 10088-87-6)
- 2-6-Dimethyl-β-cyclodextrin - Technical (CAS 51166-71-3)
- 3-Chloro-2-formyl-4-methylpyridine (CAS 884495-43-6)
- 4-(3-Methoxyphenyl)aniline (CAS 207287-79-4)
- (R)-2-(3-chloro-2,4,5-trifluorophenyl)pyrrolidine (CAS 1241683-92-0)
- 5-(4-Bromophenyl)-4H-1,2,4-triazole-3-thiol (CAS 39631-33-9)
- 2-(2-(4-Chlorobenzoyl)hydrazine-1-carbonyl)benzoic acid (CAS 60580-17-8)
- (1,7,7-trimethylnorbornan-2-yl)hydrazine (CAS 743380-66-7)
- 7-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-carbaldehyde (CAS 1638768-52-1)
- Metoclopramide Impurity 130 (CAS CATO-C4X-1415130)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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