2,4'-Difluoro-N-(2-Hydroxyethyl)Acetanilide CAS 10016-07-6
| CAS No. | 10016-07-6 |
| Molecular Formula | C10H11F2NO2 |
| Molecular Weight | 215.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,4'-Difluoro-N-(2-Hydroxyethyl)Acetanilide (CAS 10016-07-6) is a high-purity analytical reference standard with the molecular formula C10H11F2NO2 and a molecular weight of 215.20 g/mol.
2,4'-Difluoro-N-(2-Hydroxyethyl)Acetanilide (C10H11F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2,4'-Difluoro-N-(2-Hydroxyethyl)Acetanilide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11F2NO2 |
| Molecular Weight | 215.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,2-difluoro-N-methoxy-N-methyl-2-phenylacetamide (CAS 1041934-93-3)
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- 3,5-Difluoro-4-hydrazinyl-n,n-dimethylbenzamide (CAS 1342988-85-5)
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- Ethyl 2,2-difluoro-2-(5-methylpyridin-2-yl)acetate (CAS 503627-67-6)
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Recommended Standards
- Diethyl pyridin-4-ylphosphonate (CAS 37175-34-1)
- Methyl 3-amino-3-(2,6-difluorophenyl)propanoate (CAS 1009351-41-0)
- Diethyl pyridin-3-ylphosphonate (CAS 53340-10-6)
- (E)-3-(2-Hydroxyquinolin-3-yl)acrylic acid (CAS 101382-57-4)
- N-Methoxyformamide (CAS 34005-41-9)
- 1H-indazole-1-acetic acid, 6-bromo-, ethyl ester (CAS 281204-65-7)
- (3-Formylpyridin-4-yl)boronic acid (CAS 1256355-58-4)
- Topiramate Impurity 20 (CAS 38029-84-4)
- Ethyl 2-(diethylamino)-2-phenylacetate (CAS 6797-70-2)
- 3-Methylisothiazolo[5,4-b]quinoline (CAS 548930-76-3)
- 4-Chloro-6-(ethylamino)pyrimidine-5-carbonitrile (CAS 872890-12-5)
- 2-(Morpholinomethyl)pyridine (CAS 71897-59-1)
- 4-(Bromomethyl)-2-(difluoromethoxy)pyridine (CAS 1268517-84-5)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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