(3-Amino-2-chloropyridin-4-yl)methanol CAS 1002129-57-8
| CAS No. | 1002129-57-8 |
| Molecular Formula | C6H7ClN2O |
| Molecular Weight | 158.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (3-Amino-2-chloropyridin-4-yl)methanol (CAS 1002129-57-8), a certified reference material (molecular formula C6H7ClN2O, MW 158.59 g/mol) for analytical method development and quality control.
The molecular framework of (3-Amino-2-chloropyridin-4-yl)methanol (C6H7ClN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7ClN2O |
| Molecular Weight | 158.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-5-chloro-4-methylpyridin-3-ol (CAS 1003710-95-9)
- (3-Amino-6-chloropyridin-2-yl)methanol (CAS 1206454-48-9)
- (5-Amino-2-chloropyridin-4-yl)methanol (CAS 1227583-24-5)
- 4-Amino-2-chloro-3-methoxypyridine (CAS 1227600-23-8)
- (6-Amino-5-chloropyridin-3-yl)methanol (CAS 1251924-45-4)
- 2-Amino-4-chloro-6-methoxypyridine (CAS 1261628-71-0)
- (6-Amino-3-chloropyridin-2-yl)methanol (CAS 1333779-89-7)
- (2-Amino-6-chloropyridin-4-yl)methanol (CAS 1334294-36-8)
Recommended Standards
- 2-(4-Methyl-1H-pyrazol-1-yl)acetyl chloride (CAS 1001567-69-6)
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- 4-Chloroguaiacol (CAS 16766-30-6)
- O-((3-chloropyridin-4-yl)methyl)hydroxylamine (CAS 1002751-23-6)
- 3-Bromo-5-fluoro-4-methylbenzaldehyde (CAS 1370411-47-4)
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- N-Allyl-N-(4-methyloxazol-2-yl)acetamide (CAS 57068-12-9)
- 3562AF 933683-06-8 C5H9N3O N-Methyl-N-[(3-methyl-1,2,4-oxadiazol-5-yl)-methyl]amine (CAS 933683-06-8)
- 1-Cyclopentyl-4-iodo-5-(trifluoromethyl)-1H-pyrazol-3-amine (CAS 1354704-19-0)
- 7,7-Difluoro-1-methyl-3-azabicyclo[4.1.0]Heptane (CAS 1416013-70-1)
- 3-tert-butylbicyclo[1.1.1]pentane-1-carbaldehyde (CAS 125642-42-4)
- 3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole (CAS 744218-85-7)
- Serpent Peptide (CAS 823202-99-9)
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