4-(2-Chloroethoxy)phenol CAS 100238-55-9
| CAS No. | 100238-55-9 |
| Molecular Formula | C8H9ClO2 |
| Molecular Weight | 172.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(2-Chloroethoxy)phenol (CAS 100238-55-9) is a high-purity analytical reference standard with the molecular formula C8H9ClO2 and a molecular weight of 172.61 g/mol.
4-(2-Chloroethoxy)phenol (C8H9ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-(2-Chloroethoxy)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO2 |
| Molecular Weight | 172.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
Related Chloroethoxy Standards
- 2-(2-Chloroethoxy)phenol (CAS 4792-79-4)
- Bis(2-chloroethoxy)methane (CAS 111-91-1)
- 1-(2-Chloroethoxy)-2-methylbenzene (CAS 21120-79-6)
- 1-(2-Chloroethoxy)-4-methylbenzene (CAS 20764-35-6)
- 1-(2-Chloroethoxy)-4-fluorobenzene (CAS 64010-10-2)
- 1-(2-(2-Chloroethoxy)ethyl)-1h-pyrazole (CAS 108223-75-2)
- 1-(2-(2-Chloroethoxy)ethyl)-1h-1,2,4-triazole (CAS 108223-79-6)
- 2-[2-(2-Chloroethoxy)ethoxy]ethanol (CAS 5197-62-6)
Recommended Standards
- (5-Chloro-1,3-phenylene)dimethanol (CAS 1000342-26-6)
- 1-(4-Chloro-1-ethyl-1h-pyrazol-3-yl)ethan-1-one (CAS 1006434-27-0)
- 3-(Chloro-Difluoro-Methyl)Pentan-3-Ol (CAS 6302-01-8)
- 1-(4-Chloro-1-ethyl-1h-pyrazol-5-yl)ethan-1-one (CAS 1006482-81-0)
- 2-Bromo-4-(bromomethyl)-5-(difluoromethyl)-3-(trifluoromethyl)pyridine (CAS 1806858-65-0)
- Ethyl 2-(5-(trifluoromethyl)pyrimidin-2-yl)acetate (CAS 944905-47-9)
- 1-(2-Hydrazinylethyl)piperidine dihydrochloride (CAS 824-92-0)
- 4-Allyl-6-amino-2h-benzo[b][1,4]oxazin-3(4h)-one (CAS 1017195-93-5)
- 2-cyclopropyl-2-phenylethan-1-amine hydrochloride (CAS 1803609-85-9)
- 1-Cyano-N-(2-(diethylamino)-2-oxoethyl)cyclopentane-1-carboxamide (CAS 1252327-97-1)
- Ethyl 4-(3-fluorophenyl)-2,2-dimethyl-4-oxobutanoate (CAS 898753-65-6)
- Segesterone, >98% (HPLC) (CAS 7690-08-6)
- (1-(2-Hydroxyethyl)-3-methyl-1H-pyrazol-4-yl)boronic acid (CAS 2225170-81-8)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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