3-Chloro-N-(thieno[2,3-d]pyrimidin-4-yl)benzamide CAS 1003159-68-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1003159-68-9
Molecular FormulaC13H8ClN3OS
Molecular Weight289.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-N-(thieno[2,3-d]pyrimidin-4-yl)benzamide CAS 1003159-68-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-N-(thieno[2,3-d]pyrimidin-4-yl)benzamide.

3-Chloro-N-(thieno[2,3-d]pyrimidin-4-yl)benzamide (CAS 1003159-68-9) is a high-purity analytical reference standard with the molecular formula C13H8ClN3OS and a molecular weight of 289.74 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, 3-Chloro-N-(thieno[2,3-d]pyrimidin-4-yl)benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 289.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H8ClN3OS
Molecular Weight289.74 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentCl-containing
Nitrogen Atoms3
Sulfur Atoms1

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