Tetrabenazine Impurity C298 CAS 100322-43-8
| CAS No. | 100322-43-8 |
| Molecular Formula | C19H25NO3 |
| Molecular Weight | 315.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tetrabenazine Impurity C298 (CAS 100322-43-8, C19H25NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Tetrabenazine Impurity C298 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 315.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tetrabenazine Impurity C298 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H25NO3 |
| Molecular Weight | 315.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Tetrabenazine Standards
- Tetrabenazine Impurity C1327 (CAS 1556098-48-6)
- Tetrabenazine Impurity C49 (CAS 1381929-92-5)
- Tetrabenazine Impurity C9 (CAS 718635-93-9)
- Tetrabenazine Related Compound C (CAS 86457-13-8)
- Tetrabenazine (CAS 58-46-8)
- Tetrabenazine Impurity 3 (CAS 99672-64-7)
- Tetrabenazine Impurity 50( and Enantiomer) (CAS CATO-C4X-274850)
- Tetrabenazine Impurity 55-d6 (CAS CATO-C4X-274855)
Recommended Standards
- 2-((5-(3-(Thiophen-2-yl)ureido)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 1002043-11-9)
- tert-butyl (3S)-3-(aminomethyl)-3-{[(tert-butoxy)carbonyl]amino}pyrrolidine-1-carboxylate (CAS 1004992-22-6)
- Flusilazole (CAS 85509-19-9)
- 4-(Methylsulfanyl)-2-(2-phenylethenesulfonamido)butanoic acid (CAS 1008200-40-5)
- Rivaroxaban Impurity 97 (CAS 2288308-42-7)
- Raltitrexed Impurity 5 (CAS 4282-31-9)
- Crizotinib impurity 31 (CAS CATO-C4X-102531)
- 3-Ethyl-1-methyl-1H-pyrrole (CAS 53871-25-3)
- 4-(1H-Pyrrolo[2,3-b]pyridin-2-yl)phenol (CAS 1346526-26-8)
- H-Asp-AMC (CAS 219138-13-3)
- O,O,O-trimethyl phosphorothioate (CAS 152-18-1)
- methyl 3-formylcyclobutanecarboxylate (CAS 1784306-12-2)
- Glabranin (CAS 41983-91-9)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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