Methyl 6-hydroxypyrazolo[1,5-a]pyridine-3-carboxylate CAS 1003581-82-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1003581-82-5
Molecular FormulaC9H8N2O3
Molecular Weight192.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 6-hydroxypyrazolo[1,5-a]pyridine-3-carboxylate CAS 1003581-82-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 6-hydroxypyrazolo[1,5-a]pyridine-3-carboxylate.

Methyl 6-hydroxypyrazolo[1,5-a]pyridine-3-carboxylate (CAS 1003581-82-5), molecular formula C9H8N2O3 and molecular weight 192.17 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, Methyl 6-hydroxypyrazolo[1,5-a]pyridine-3-carboxylate (C9H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 192.17 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H8N2O3
Molecular Weight192.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Nitrogen Atoms2

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