Tert-butyl 3-hydroxy-4-[4-(trifluoromethyl)phenyl]piperidine-1-carboxylate CAS 1004619-28-6
| CAS No. | 1004619-28-6 |
| Molecular Formula | C17H22F3NO3 |
| Molecular Weight | 345.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 345.36 g/mol gives Tert-butyl 3-hydroxy-4-[4-(trifluoromethyl)phenyl]piperidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tert-butyl 3-hydroxy-4-[4-(trifluoromethyl)phenyl]piperidine-1-carboxylate (CAS 1004619-28-6) is a high-purity analytical reference standard with the molecular formula C17H22F3NO3 and a molecular weight of 345.36 g/mol.
The molecular framework of Tert-butyl 3-hydroxy-4-[4-(trifluoromethyl)phenyl]piperidine-1-carboxylate (C17H22F3NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Tert-butyl 3-hydroxy-4-[4-(trifluoromethyl)phenyl]piperidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H22F3NO3 |
| Molecular Weight | 345.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Samidorphan Impurity 6 (CAS CATO-C4X-33096)
- Tert-butyl (3S,4R)-3-(hydroxymethyl)-4-(2-(trifluoromethyl)phenyl)pyrrolidine-1-carboxylate (CAS 1186647-92-6)
- Vonoprazan Fumarate impurity 124 (CAS CATO-C4X-1020124)
- Tert-butyl 3-hydroxy-4-(3-(trifluoromethyl)phenyl)piperidine-1-carboxylate (CAS 1187173-60-9)
- (2R,3S,4S,5R,6S)-4,5-bis(benzyloxy)-2-((benzyloxy)methyl)-6-(ethylthio)tetrahydro-2H-pyran-3-ol (CAS 152964-77-7)
- N1-(4-((2-Carbamoylpyridin-4-yl)oxy)phenyl)-N3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)isophthalamide (CAS 1334499-71-6)
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- Kaempferol-3-O-(6-Malonyl-Glucoside) (CAS 81149-02-2)
- 2,3,5-Trifluoro-6-methoxypyridine (CAS 3746-18-7)
- tert-Butyl (3-methylenecyclobutyl)carbamate (CAS 130369-04-9)
- 4-(bromomethyl)-6-(trifluoromethyl)-1H-indole (CAS 2306269-46-3)
- Ozagrel Impurity 8 (CAS 141286-90-0)
- N-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-4-methyl-1,2,3-thiadiazole-5-carboxamide (CAS 1207047-39-9)
- Galanin-Like Peptide (porcine) trifluoroacetate salt (CAS 245114-96-9)
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