4-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-pyrimidine-2-thiol CAS 1004643-65-5
| CAS No. | 1004643-65-5 |
| Molecular Formula | C4H4N4O4 |
| Molecular Weight | 172.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-pyrimidine-2-thiol.
4-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-pyrimidine-2-thiol (CAS 1004643-65-5), molecular formula C4H4N4O4 and molecular weight 172.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-pyrimidine-2-thiol (C4H4N4O4) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-pyrimidine-2-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H4N4O4 |
| Molecular Weight | 172.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 4 |
Recommended Standards
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