4-(5-Chloro-2-fluorophenyl)piperidine CAS 1004852-70-3
| CAS No. | 1004852-70-3 |
| Molecular Formula | C11H13ClFN |
| Molecular Weight | 213.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(5-Chloro-2-fluorophenyl)piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(5-Chloro-2-fluorophenyl)piperidine (CAS 1004852-70-3) is a high-purity analytical reference standard with the molecular formula C11H13ClFN and a molecular weight of 213.68 g/mol.
The molecular framework of 4-(5-Chloro-2-fluorophenyl)piperidine (C11H13ClFN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H13ClFN |
| Molecular Weight | 213.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- (E)-6-chlorothiochroman-4-one oxime (CAS 1029134-50-6)
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- 2-Ethylbutane-1-sulfonyl chloride (CAS 854463-29-9)
- Arotinolol Impurity 14 (CAS 1701418-50-9)
- 3-{[(tert-Butoxycarbonyl)amino]methyl}[1,1-biphenyl]-4-carboxylic acid (CAS 193151-98-3)
- (E)-2,2'-((2-(2-(8-(Bis(carboxymethyl)amino)-6-methoxyquinolin-2-yl)vinyl)phenyl)azanediyl)diacetic acid (CAS 86277-62-5)
- 3-Acetyl-5-nitrobenzaldehyde (CAS 1393562-14-5)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
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