4-(Methylsulfanyl)-3-(trifluoromethoxy)phenylboronic acid CAS 1005206-27-8
| CAS No. | 1005206-27-8 |
| Molecular Formula | C8H8BF3O3S |
| Molecular Weight | 252.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(Methylsulfanyl)-3-(trifluoromethoxy)phenylboronic acid is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(Methylsulfanyl)-3-(trifluoromethoxy)phenylboronic acid (CAS 1005206-27-8), molecular formula C8H8BF3O3S and molecular weight 252.02 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Methylsulfanyl)-3-(trifluoromethoxy)phenylboronic acid (C8H8BF3O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Methylsulfanyl)-3-(trifluoromethoxy)phenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8BF3O3S |
| Molecular Weight | 252.02 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Methylsulfanyl Standards
- 7028-70-8 Ethyl 4-[4-(methylsulfanyl)phenyl]-4-oxobutanoate DTXSID20645598 (CAS 7028-70-8)
- 1-[2-(Methylsulfanyl)thieno[2,3-d]pyrimidin-4-yl]pyrrolidine (CAS 383146-89-2)
- 1-[2-(Methylsulfanyl)thieno[3,2-d]pyrimidin-4-yl]pyrrolidine (CAS 343374-13-0)
- 4-Ethyl-5-[2-(methylsulfanyl)phenyl]-4H-1,2,4-triazole-3-thiol (CAS 338967-83-2)
- 3-(Methylsulfanyl)-2-phenylquinoline (CAS 400079-67-6)
- 1-[3-(methylsulfanyl)phenyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 63674-52-2)
- 1-[4-(methylsulfanyl)phenyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 63674-53-3)
- 76360-89-9 7-(Methylsulfanyl)-1-(propan-2-yl)-2H-pyrimido[4,5-d][1,3]oxazine-2,4(1H)-dione DTXSID70608754 (CAS 76360-89-9)
Recommended Standards
- 7-Bromo-2,2-difluorobenzo[d][1,3]dioxol-4-amine (CAS 2231233-77-3)
- 4-Fluoro-3-iodoanisole (CAS 1028263-94-6)
- Methyl 5-iodofuran-2-carboxylate (CAS 2527-98-2)
- (2-Fluoro-4-iodophenyl)methanol (CAS 1039646-78-0)
- 2,2-Dichloro-N-[4-(4-methylpiperazin-1-yl)phenyl]acetamide (CAS 303150-59-6)
- Methyl (S)-3-amino-2-phenylpropanoate hydrochloride (CAS 909397-88-2)
- 4-Bromo-3-cyclopropoxy-N-methylpicolinamide (CAS 1243476-41-6)
- 1-methyl-1H-imidazo[4,5-b]pyridine-2-carbaldehyde (CAS 57806-04-9)
- Azidoethyl-SS-propionic acid (CAS 2228857-32-5)
- 5-(4-Propylpiperazin-1-yl)-1,3,4-thiadiazol-2-amine (CAS 932347-85-8)
- (E)-1-(piperidin-1-yl)-3-(quinolin-3-yl)prop-2-en-1-one (CAS 478039-40-6)
- Cefdinir USP Related Compound A (CAS 178422-42-9)
- Methyl 4-6-O-benzylidene-3-O-(b-D-glucopyranoside)-α-D-glucopyranoside (CAS 72656-05-4)
- Hexapeptide-11 (CAS 100684-36-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com