Methyl 2-(1H-1,2,4-triazol-1-yl)propanoate CAS 100554-35-6

Purity 97%+In StockPharmaceutical Standards
CAS No.100554-35-6
Molecular FormulaC6H9N3O2
Molecular Weight155.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 2-(1H-1,2,4-triazol-1-yl)propanoate CAS 100554-35-6 chemical structure

Description

The occurrence of Methyl 2-(1H-1,2,4-triazol-1-yl)propanoate is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Methyl 2-(1H-1,2,4-triazol-1-yl)propanoate (CAS 100554-35-6) is a high-purity analytical reference standard with the molecular formula C6H9N3O2 and a molecular weight of 155.15 g/mol.

The molecular framework of Methyl 2-(1H-1,2,4-triazol-1-yl)propanoate (C6H9N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Methyl 2-(1H-1,2,4-triazol-1-yl)propanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H9N3O2
Molecular Weight155.15 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Nitrogen Atoms3

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