7-Trifluoromethyl-1H-benzoimidazol-2-ylamine CAS 10057-45-1
| CAS No. | 10057-45-1 |
| Molecular Formula | C8H6F3N3 |
| Molecular Weight | 201.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 7-Trifluoromethyl-1H-benzoimidazol-2-ylamine (CAS 10057-45-1), a certified reference material (molecular formula C8H6F3N3, MW 201.15 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 7-Trifluoromethyl-1H-benzoimidazol-2-ylamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 201.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H6F3N3 |
| Molecular Weight | 201.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 6-(Trifluoromethyl)-1H-indazol-5-amine (CAS 1000373-75-0)
- 7-(Trifluoromethyl)imidazo[1,5-a]pyridin-3-amine (CAS 1005514-81-7)
- 2-(Trifluoromethyl)-1H-indol-4-ol (CAS 1016241-93-2)
- 4-(Trifluoromethyl)-1H-indazol-6-amine (CAS 1169788-34-4)
- 2-(trifluoromethyl)-1H-Pyrrolo[2,3-b]pyridin-5-amine (CAS 1186502-40-8)
- 6-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridin-3-amine (CAS 1190311-51-3)
- 5-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridin-3-amine (CAS 1190319-60-8)
- 6-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1190320-36-5)
Recommended Standards
- 2-Amino-5-(trifluoromethyl)benzoimidazole (CAS 10057-46-2)
- 2,4,5-Trifluoro-3-methoxy-6-methylbenzonitrile (CAS 1003708-50-6)
- 2-Amino-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 1005785-87-4)
- Ethyl 5-fluoro-4-hydroxy-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 1000340-08-8)
- 7-Fluorobenzo[d]isothiazol-4-ol (CAS 934180-40-2)
- N-Isobutyl-2-nitrobenzamide (CAS 88358-27-4)
- 3-Ethynyl-2-(trifluoromethyl)thiophene (CAS 1857038-92-6)
- (3-Ethoxy-4-methoxyphenyl)methanamine hydrochloride (CAS 1443425-21-5)
- 5-Methyl-1H-indole-2-carboxylic acid (CAS 10241-97-1)
- (5-Fluoro-2-methylphenyl)trimethylsilane (CAS 1314911-18-6)
- 3-Cyano-1-(4-fluorophenyl)-2(1H)-pyridinone (CAS 929000-74-8)
- 1-(5-Methyl-3-phenyl-1,2-oxazole-4-carbonyl)piperidine (CAS 328045-80-3)
- 2-(Isopentyloxy)nicotinic acid (CAS 1016678-87-7)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
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