4-[1-[tert-Butyl(dimethyl)silyl]oxy-2-methylpropan-2-yl]benzoic acid CAS 1005786-00-4
| CAS No. | 1005786-00-4 |
| Molecular Formula | C17H28O3Si |
| Molecular Weight | 308.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[1-[tert-Butyl(dimethyl)silyl]oxy-2-methylpropan-2-yl]benzoic acid (CAS 1005786-00-4), molecular formula C17H28O3Si and molecular weight 308.49 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, a hydroxyl group, an ether linkage, 4-[1-[tert-Butyl(dimethyl)silyl]oxy-2-methylpropan-2-yl]benzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 308.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H28O3Si |
| Molecular Weight | 308.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
Recommended Standards
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- (Z)-5-Chloro-6-(1-fluoro-2-iodovinyl)nicotinonitrile (CAS 2230615-72-0)
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- 3-Bromo-2,6,8-trichloroquinoline (CAS 1447958-98-6)
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- Naphthalenesulfonic acid, methyl-, sodium salt (CAS 26264-58-4)
- Methyl 5-amino-4-hydroxynicotinate (CAS 2092500-23-5)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
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