7-Chloro-8-methyl-1,2,3,4-tetrahydroquinoline CAS 100642-29-3
| CAS No. | 100642-29-3 |
| Molecular Formula | C10H12ClN |
| Molecular Weight | 181.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Chloro-8-methyl-1,2,3,4-tetrahydroquinoline.
7-Chloro-8-methyl-1,2,3,4-tetrahydroquinoline (CAS 100642-29-3) is a high-purity analytical reference standard with the molecular formula C10H12ClN and a molecular weight of 181.66 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 7-Chloro-8-methyl-1,2,3,4-tetrahydroquinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-Chloro-8-methyl-1,2,3,4-tetrahydroquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN |
| Molecular Weight | 181.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (R)-7-Chloro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1055949-63-7)
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- 7-Chloro-8-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1066822-69-2)
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Recommended Standards
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Why CATO?
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