5-{[4-bromo-3,5-bis(difluoromethyl)-1h-pyrazol-1-yl]methyl}furan-2-carboxylic acid CAS 1006447-74-0
| CAS No. | 1006447-74-0 |
| Molecular Formula | C11H7BrF4N2O3 |
| Molecular Weight | 371.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-{[4-bromo-3,5-bis(difluoromethyl)-1h-pyrazol-1-yl]methyl}furan-2-carboxylic acid.
5-{[4-bromo-3,5-bis(difluoromethyl)-1h-pyrazol-1-yl]methyl}furan-2-carboxylic acid (CAS 1006447-74-0), molecular formula C11H7BrF4N2O3 and molecular weight 371.08 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 5-{[4-bromo-3,5-bis(difluoromethyl)-1h-pyrazol-1-yl]methyl}furan-2-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 371.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-{[4-bromo-3,5-bis(difluoromethyl)-1h-pyrazol-1-yl]methyl}furan-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7BrF4N2O3 |
| Molecular Weight | 371.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
- 2-(2-Bromo-4-fluorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244088-23-9)
- 2-(3-Bromo-4-fluorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244084-81-7)
- 2-(4-Bromo-2-fluorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244087-64-5)
- 2-(5-Bromo-2-fluorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244087-61-2)
- 4-Bromo-2-(((4-bromo-3-methylphenyl)amino)methyl)phenol (CAS 329777-39-1)
- 7-Bromo-2-(2,6-dichlorophenyl)-2,3-dihydroquinolin-4(1H)-one (CAS 882854-45-7)
- 1-(4-Bromo-5-methyl-3-(perfluoropropyl)-1H-pyrazol-1-yl)ethan-1-one (CAS 808764-22-9)
- 1-Acetyl-4-bromo-5(3)-heptafluoropropyl-3(5)-methylpyrazole (CAS 232278-00-1)
Recommended Standards
- Bis-(6-bromopyridin-2-ylmethyl)-methylamine (CAS 845621-72-9)
- 2,5-Dibromo-N-isobutylbenzenesulfonamide (CAS 1018213-48-3)
- 2,5-Dibromo-N,N-diethylbenzenesulfonamide (CAS 446308-89-0)
- 3,7-Dibromo-10-methyl-10H-phenothiazine (CAS 34964-70-0)
- 6-Chloro-1H-indole-3-carbonyl chloride (CAS 1260794-86-2)
- 2-((2-(Trimethylsilyl)ethoxy)methyl)-2H-indazol-4-amine (CAS 921600-51-3)
- n-Ethyl-2-iodoaniline (CAS 133286-16-5)
- Thiobutyl butyrolactone (CAS 902525-29-5)
- 2-(6-ethynyl-3-pyridyl)acetic acid (CAS 1211540-18-9)
- 2-(Ethoxycarbonyl)spiro[3.3]heptane-2-carboxylic acid (CAS 2116201-81-9)
- 3-(3-Ethoxy-propyl)-2-mercapto-3H-quinazolin-4-one (CAS 380436-96-4)
- N-Iodoacetyltyramine (CAS 53527-07-4)
- 4-Fluoro-3-hydroxybenzyl alcohol (CAS 934241-78-8)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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