3-Ethoxy-2-fluoro-3-oxopropanoic acid CAS 100701-49-3
| CAS No. | 100701-49-3 |
| Molecular Formula | C5H7FO4 |
| Molecular Weight | 150.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Ethoxy-2-fluoro-3-oxopropanoic acid (CAS 100701-49-3), molecular formula C5H7FO4 and molecular weight 150.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Ethoxy-2-fluoro-3-oxopropanoic acid (C5H7FO4) is characterized by a carbohydrate-derived structure, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-Ethoxy-2-fluoro-3-oxopropanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7FO4 |
| Molecular Weight | 150.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
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