5-(Trifluoromethoxy)-2-(trifluoromethyl)-1H-indole CAS 1007235-31-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1007235-31-5
Molecular FormulaC10H5F6NO
Molecular Weight269.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(Trifluoromethoxy)-2-(trifluoromethyl)-1H-indole CAS 1007235-31-5 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

5-(Trifluoromethoxy)-2-(trifluoromethyl)-1H-indole (CAS 1007235-31-5), molecular formula C10H5F6NO and molecular weight 269.14 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(Trifluoromethoxy)-2-(trifluoromethyl)-1H-indole (C10H5F6NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC10H5F6NO
Molecular Weight269.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms1

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