Methyl 1-(4-cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)-1h-pyrazole-3-carboxylate CAS 1007344-24-2
| CAS No. | 1007344-24-2 |
| Molecular Formula | C13H11F3N4O2 |
| Molecular Weight | 312.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 1-(4-cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)-1h-pyrazole-3-carboxylate (C13H11F3N4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Methyl 1-(4-cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)-1h-pyrazole-3-carboxylate (CAS 1007344-24-2) is a high-purity analytical reference standard with the molecular formula C13H11F3N4O2 and a molecular weight of 312.25 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 1-(4-cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)-1h-pyrazole-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11F3N4O2 |
| Molecular Weight | 312.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Methyl Standards
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- 1-Cyclopropyl-3-(3-((4-fluorobenzyl)oxy)phenyl)-3-hydroxyprop-2-en-1-one (CAS 860789-18-0)
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Recommended Standards
- 5-Hydroxy Flunixin (CAS 75369-61-8)
- <I>N</I>-acetyl-<SC>D</SC>-neuraminic acid-1,2,3-<SUP>13</SUP>C<SUB>3</SUB> (CAS 1172608-56-8)
- N-(4-methoxyphenyl)-2-nitro-4-(trifluoromethyl)aniline (CAS 849-58-1)
- 1-(4-Bromo-2-(methoxymethyl)phenyl)-2-ethylpiperidine (CAS 1229608-68-7)
- 4,7-diazaspiro[2.5]octane-5,8-dione (CAS 129306-17-8)
- cis-1,3-dihydroxycyclobutane-1-carboxylic acid (CAS 2227198-91-4)
- 2,3,5-Trifluoro-4-piperidin-1-ylbenzoic acid (CAS 1858255-57-8)
- Salvianolic acid L (CAS 389065-74-1)
- 1-(1,3,4-thiadiazol-2-ylthio)acetone (CAS 1000932-13-7)
- 1,2-Dimethylquinolin-4(1H)-one (CAS 6760-40-3)
- Sodium 2-(hydroxybis(4-(phosphonatooxy)phenyl)methyl)benzoate hydrate (CAS 2382-56-1)
- 2-(Cyclopropylamino)benzonitrile (CAS 675575-45-8)
- Ethoxymethyl propionate (CAS 54078-53-4)
- SAMS Peptide (CAS 125911-68-4)
Why CATO?
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