5-(3-methoxybenzyl)-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one CAS 1008035-84-4
| CAS No. | 1008035-84-4 |
| Molecular Formula | C20H19F3N2O2 |
| Molecular Weight | 376.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(3-methoxybenzyl)-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one (CAS 1008035-84-4) is a high-purity analytical reference standard with the molecular formula C20H19F3N2O2 and a molecular weight of 376.37 g/mol.
The molecular framework of 5-(3-methoxybenzyl)-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one (C20H19F3N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(3-methoxybenzyl)-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H19F3N2O2 |
| Molecular Weight | 376.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- (2,5-Dibromophenyl)diphenylphosphineoxide (CAS 1629166-79-5)
- 5-Bromo-7-chloro-3-methyl-1-benzofuran-2-carboxylic acid (CAS 1094288-67-1)
- N-Benzyl-2-(4-phenylpiperazin-1-yl)quinazolin-4-amine (CAS 166039-49-2)
- (E)-2,6-Dibenzhydryl-4-methoxy-N-(1-(9-(2,4,6-triisopropylphenyl)-1,10-phenanthrolin-2-yl)ethylidene)aniline (CAS 2751681-03-3)
- 1-[2-(Methylsulfonyl)-4-nitrophenyl]pyrrolidine-2-carboxylic acid (CAS 1452572-57-4)
- 3,3-Dichloropiperidin-2-one (CAS 41419-12-9)
- Itraconazole Impurity 85 (CAS CATO-C4X-149785)
- 3-(2-(3-Methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)benzoic acid (CAS 314291-23-1)
- 19-Methoxy-19-oxononadecanoic acid (CAS 72849-43-5)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
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