2'-Acetyl-[1,1'-biphenyl]-2-carbaldehyde CAS 100914-80-5
| CAS No. | 100914-80-5 |
| Molecular Formula | C15H12O2 |
| Molecular Weight | 224.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2'-Acetyl-[1,1'-biphenyl]-2-carbaldehyde.
CATO supplies 2'-Acetyl-[1,1'-biphenyl]-2-carbaldehyde (CAS 100914-80-5), a certified reference material (molecular formula C15H12O2, MW 224.25 g/mol) for analytical method development and quality control.
The molecular framework of 2'-Acetyl-[1,1'-biphenyl]-2-carbaldehyde (C15H12O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12O2 |
| Molecular Weight | 224.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
Related Acetyl Standards
- 2-([1,1'-Biphenyl]-4-yl)malonaldehyde (CAS 125507-91-7)
- 4'-Acetyl[1,1'-biphenyl]-2-carbaldehyde (CAS 150970-51-7)
- 2'-Acetyl[1,1'-biphenyl]-3-carbaldehyde (CAS 400747-72-0)
- 3-([1,1'-Biphenyl]-3-yl)acrylic acid (CAS 60521-26-8)
- 3'-Acetyl-[1,1'-biphenyl]-2-carbaldehyde (CAS 400745-14-4)
- 3'-Acetyl-[1,1'-biphenyl]-4-carbaldehyde (CAS 400750-70-1)
- 4'-Acetyl-[1,1'-biphenyl]-3-carbaldehyde (CAS 400747-38-8)
- 4'-Acetyl-[1,1'-biphenyl]-4-carbaldehyde (CAS 230647-85-5)
Recommended Standards
- Furan-3-yl(naphthalen-2-yl)methanol (CAS 1008533-24-1)
- Furan-3-yl(naphthalen-1-yl)methanol (CAS 1016925-55-5)
- Amisulpride Impurity 22 (CAS 1823413-49-5)
- 3-(3,4-Dimethoxy-2-methylphenyl)propanoic acid (CAS 1017073-96-9)
- N1-Ethyl-N1-(4-fluorobenzyl)ethane-1,2-diamine (CAS 61694-94-8)
- 5-Chloro-2-(methylthio)-N-(5-(propylthio)-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide (CAS 833434-85-8)
- Naphth[1,2-a]anthracene (CAS 195-06-2)
- N,N-dimethylpyrimidin-4-amine (CAS 31401-45-3)
- 1-Amino-3-methyl-1H-pyrrole-2-carboxamide hydrochloride (CAS 1956355-16-0)
- Lifitegrast Impurity 172 (CAS CATO-C4X-2409172)
- 2-(Bromomethyl)-6-(difluoromethyl)-5-iodopyridine-3-acetonitrile (CAS 1804868-12-9)
- N-(2-{[2,5-bis(2,2,2-trifluoroethoxy)phenyl]formamido}ethyl)-2-chloroacetamide (CAS 338404-61-8)
- 5-Chloro-3-(thiophen-2-ylmethyl)-1,2,4-thiadiazole (CAS 1338218-71-5)
- Peptide Impurity 82 (CAS 10491-78-8)
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