[6-cyclopropyl-4-(methoxycarbonyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid CAS 1011396-63-6
| CAS No. | 1011396-63-6 |
| Molecular Formula | C14H15N3O4 |
| Molecular Weight | 289.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [6-cyclopropyl-4-(methoxycarbonyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid.
CATO supplies [6-cyclopropyl-4-(methoxycarbonyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1011396-63-6), a certified reference material (molecular formula C14H15N3O4, MW 289.29 g/mol) for analytical method development and quality control.
Structurally, [6-cyclopropyl-4-(methoxycarbonyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (C14H15N3O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 289.29 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H15N3O4 |
| Molecular Weight | 289.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
Related cyclopropyl Standards
- 7-Cyclopropyl-2,4-dioxo-1-propyl-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-5-carboxylic acid (CAS 1000932-48-8)
- 2-[3-cyclopropyl-4-(methoxycarbonyl)-6-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1018141-95-1)
- Ethyl 7-cyclopropyl-1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-5-carboxylate (CAS 1217863-09-6)
- N-cyclopropyl-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide (CAS 338400-59-2)
- Ethyl 3-cyclopropyl-6-hydroxy-1-propyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1174839-56-5)
- Cyclopropyl(4-(4-nitrophenyl)-1,4-diazepan-1-yl)methanone (CAS 1286728-06-0)
- N-Cyclopropyl-2-(2,5-dioxopyrrolidin-1-yl)-N-((1-methyl-1H-pyrrol-2-yl)methyl)acetamide (CAS 1286728-96-8)
- N-Cyclopropyl-3-(1H-indol-4-yl)imidazo[1,2-a]pyrazin-8-amine (CAS 825630-54-4)
Recommended Standards
- 5-((4-Methoxybenzyl)carbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid (CAS 1006476-87-4)
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-3-methoxy-1-methyl-1H-pyrazole-4-carboxamide (CAS 1014069-03-4)
- 2-((3,5-Dimethyl-4-nitro-1h-pyrazol-1-yl)methyl)benzohydrazide (CAS 1001500-02-2)
- 3-(3-Methyl-3H-diazirin-3-yl)-N-((2S,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl)propanamide (CAS 1015698-41-5)
- 1-(2,4-Difluorophenyl)-4,4,4-trifluorobutane-1,3-dione (CAS 64287-18-9)
- 1-(1-Amino-1H-pyrrol-2-yl)ethanone (CAS 158883-64-8)
- 2-(3,4-Difluorophenoxy)-3,3,3-trifluoropropan-1-amine (CAS 886764-15-4)
- N-(tert-butyl)-3,5-dimethylaniline (CAS 110993-40-3)
- 2-(Tert-butoxy)-4-chloroaniline (CAS 1181302-84-0)
- Boron sub-2,3-naphthalocyanine chloride (CAS 142710-56-3)
- 3-(Octyloxy)azetidine (CAS 1410002-81-1)
- Ethyl 5-(trifluoromethyl)pyrimidine-4-carboxylate (CAS 1806545-85-6)
- 5-ethyl-3-{octahydropyrrolo[3,4-c]pyrrol-2-ylmethyl}-1,2,4-oxadiazole dihydrochloride (CAS 1311318-14-5)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
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