3-cyclopropyl-1-(4-fluorophenyl)-6-thien-2-yl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid CAS 1011397-26-4
| CAS No. | 1011397-26-4 |
| Molecular Formula | C20H14FN3O2S |
| Molecular Weight | 379.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-cyclopropyl-1-(4-fluorophenyl)-6-thien-2-yl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid.
CATO supplies 3-cyclopropyl-1-(4-fluorophenyl)-6-thien-2-yl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-26-4), a certified reference material (molecular formula C20H14FN3O2S, MW 379.41 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 3-cyclopropyl-1-(4-fluorophenyl)-6-thien-2-yl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 379.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H14FN3O2S |
| Molecular Weight | 379.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related cyclopropyl Standards
- N-Cyclopropyl-4-methyl-3-(4-phenylquinazolin-7-yl)benzamide (CAS 832114-25-7)
- 2-(3-Cyclopropyl-6-(1,5-dimethyl-1h-pyrazol-4-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 1006444-33-2)
- 2-(3-Cyclopropyl-6-(1-ethyl-1h-pyrazol-4-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 1006477-52-6)
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- Cyclopropyl 2-(2-methoxyphenyl)ethyl ketone (CAS 898774-25-9)
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- 9-Cyclopropyl-6,8-difluoro-7-(piperazin-1-yl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione (CAS 111279-49-3)
- N-Cyclopropyl-4-{[(4-methylphenyl)methyl]sulfanyl}-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaen-6-amine (CAS 478029-91-3)
Recommended Standards
- Fmoc-cyclohexyl-Gly-OH (CAS 161321-36-4)
- 1-(2H-1,3-Benzodioxol-5-yl)-N-[5-(4-fluorophenyl)-1H,4H-thieno[2,3-d]pyrimidin-4-ylidene]methanamine (CAS 1030123-90-0)
- Z-Gly-Gly-Leu-OH (CAS 13347-77-8)
- Methyl 4-{3-[1-(3-nitro-2-pyridinyl)-4-piperidinyl]-1H-pyrazol-5-yl}phenyl ether (CAS 1031208-10-2)
- [4-(Aminomethyl)piperidin-1-yl](4-fluorophenyl)methanone hydrochloride (CAS 1286272-94-3)
- (2R,3R,4R,5R)-2-(4-Methoxyphenyl)-1,5-dimethylpyrrolidine-3,4-diol (CAS 32490-07-6)
- 4-Ethyl-6-methyldibenzothiophene (CAS 132034-90-3)
- Methyl 4-hydroxy-3-(methylcarbamoyl)benzoate (CAS 2306054-93-1)
- 6-Hydroxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-Toluate (CAS 1159977-41-9)
- 4-(2-Chlorophenylsulfanyl)Piperidine Hydrochloride (CAS 101798-68-9)
- 1-(Adamantan-1-yl)-4-bromo-1h-pyrazole-3-carboxylic acid (CAS 444010-37-1)
- N-(1-Methoxyethyl)acetamide (CAS 55204-51-8)
- trifluoroacetic acid 2-methoxyethyl (3S)-3-(aminomethyl)-5-methylhexanoate (CAS 1955473-98-9)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
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