Methyl 1-(2-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate CAS 1011397-81-1
| CAS No. | 1011397-81-1 |
| Molecular Formula | C18H12FN3O2S |
| Molecular Weight | 353.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Methyl 1-(2-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011397-81-1), molecular formula C18H12FN3O2S and molecular weight 353.37 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 1-(2-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (C18H12FN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Methyl 1-(2-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12FN3O2S |
| Molecular Weight | 353.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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- N-(4-Fluorophenyl)-5-methyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574583-79-1)
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- 1-((2-(4-Fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid (CAS 727977-52-8)
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Recommended Standards
- ethyl 4-(3-(1,3-dioxoisoindolin-2-yl)propoxy)benzoate (CAS 100840-55-9)
- N-(3-(3-(4-Methoxyphenyl)-6-oxopyridazin-1(6H)-yl)propyl)furan-2-carboxamide (CAS 1021224-39-4)
- Efinaconazole Impurity 2 (CAS 135133-23-2)
- 10,11-Dimethoxy-8-oxo-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline-13-carboxylic acid (CAS 1119451-13-6)
- 3-(4-Chlorophenyl)-1-(phenylamino)-1H-pyrrole-2,5-dione (CAS 49811-68-9)
- 1,2,3,4-Tetrahydropyrido[2,3-d]pyridazin-5(6H)-one hydrochloride (CAS 1956341-48-2)
- 3-(Dimethylamino)-1-(4-hydroxyphenyl)propan-1-one (CAS 35076-36-9)
- (5-Pentyloxazol-2-yl)methanamine (CAS 2586281-62-9)
- 6-(4-Chlorophenyl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 886503-59-9)
- Diallyl phenylphosphonate (CAS 2948-89-2)
- Ethyl 4,4,4-trifluoro-2-methoxy-3-oxobutanoate (CAS 75631-71-9)
- 1060817-53-9 8296AC C8H5F2NO3 [(3,5-Difluorophenyl)amino](oxo)acetic acid (CAS 1060817-53-9)
- Eptifibatide Impurity 7 (CAS CATO-C4X-23457)
- Custom peptides (CAS CATO-CPTD788509)
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