1-(2-Chlorobenzyl)-3-methyl-6-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid CAS 1011399-97-5
| CAS No. | 1011399-97-5 |
| Molecular Formula | C21H16ClN3O2 |
| Molecular Weight | 377.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Chlorobenzyl)-3-methyl-6-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid.
CATO supplies 1-(2-Chlorobenzyl)-3-methyl-6-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011399-97-5), a certified reference material (molecular formula C21H16ClN3O2, MW 377.82 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-(2-Chlorobenzyl)-3-methyl-6-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 377.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H16ClN3O2 |
| Molecular Weight | 377.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorobenzyl Standards
- 1-(3-Chlorobenzyl)-3-methyl-6-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011398-52-9)
- 1-(4-chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011400-09-1)
- 2-Chlorobenzyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)propanoate (CAS 339010-48-9)
- 3-Chlorobenzyl 1-(3-chlorobenzyl)piperidine-2-carboxylate (CAS 1261229-53-1)
- 2-Chlorobenzyl 1-(2-chlorobenzyl)piperidine-4-carboxylate (CAS 1261230-59-4)
- 3-Chlorobenzyl 1-(3-chlorobenzyl)piperidine-3-carboxylate (CAS 1353980-13-8)
- 1-Benzyl-4-((4-chlorobenzyl)thio)phthalazine (CAS 338417-98-4)
- 2-((2-Chlorobenzyl)thio)-4,5-diphenyl-1H-imidazole (CAS 339277-36-0)
Recommended Standards
- 2-((1-Cyano-1-cyclopropylethyl)amino)-2-oxoethyl (2-chlorobenzoyl)alaninate (CAS 1008707-52-5)
- (2S)-N-(3-chloro-4-fluorophenyl)-2-[[[(tetrahydro-1,1-dioxido-3-thienyl)amino]carbonyl]amino]-Propanamide (CAS 1212437-54-1)
- N-(8-chloro-2,3-dihydro-[1,4]dioxino[2,3-g]quinoxalin-7-yl)benzenesulfonamide (CAS 329269-15-0)
- CU CPT 4a (CAS 1279713-77-7)
- (S)-N-Cyclopentyl-N-(2,3-dichlorobenzyl)pyrrolidin-3-amine (CAS 820980-19-6)
- (3-Ethynylphenyl)dimethylphosphine oxide (CAS 2287286-68-2)
- 2-((4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxy-5-methylphenyl)acetamide (CAS 763108-70-9)
- 2-(Benzo[d]thiazol-2-yl)acetyl chloride (CAS 500532-59-2)
- 5-Chloro-4-hydroxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 1248288-65-4)
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- 5-(Oxiran-2-ylmethyl)benzo[d][1,3]dioxole (CAS 7470-44-2)
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