4-[(2-methoxyphenyl)methyl]-1-{[(4-methylphenyl)methyl]sulfanyl}-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-5-one CAS 1012760-54-1
| CAS No. | 1012760-54-1 |
| Molecular Formula | C25H22N4O2S |
| Molecular Weight | 442.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[(2-methoxyphenyl)methyl]-1-{[(4-methylphenyl)methyl]sulfanyl}-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-5-one (CAS 1012760-54-1), molecular formula C25H22N4O2S and molecular weight 442.53 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 4-[(2-methoxyphenyl)methyl]-1-{[(4-methylphenyl)methyl]sulfanyl}-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-5-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 442.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[(2-methoxyphenyl)methyl]-1-{[(4-methylphenyl)methyl]sulfanyl}-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H22N4O2S |
| Molecular Weight | 442.53 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related methoxyphenyl Standards
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Recommended Standards
- N1,N1,N3,N3-tetrakis(pyrazin-2-ylmethyl)propane-1,3-diamine (CAS 493045-87-7)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(acetamidothio)-3-methylbutanoic acid (CAS 1246647-73-3)
- AZ-6197, >98% (HPLC) (CAS 2023003-94-1)
- Bis(4-(quinoxalin-2-yl)phenyl)sulfane (CAS 13107-66-9)
- 4-[(4-Chlorobenzenesulfonyl)methyl]-6-[(4-chlorophenyl)sulfanyl]-2-methylpyrimidine (CAS 338960-45-5)
- Ethyl 3-Chloro-alpha,alpha-difluorophenylacetate (CAS 135334-14-4)
- (R)-2-(tert-butoxycarbonyl)isoindoline-1-carboxylic acid (CAS 1212086-74-2)
- Gamma-methyl-alpha-(trifluoromethyl)-gamma-butyrolactone (CAS 139547-12-9)
- m-PEG3-NHS ester (CAS 876746-59-7)
- N-(3-Cyanothiophen-2-yl)-3-(ethylsulfonyl)benzamide (CAS 898459-46-6)
- 5-ethyl-3-(pyrrolidin-2-yl)-1,2,4-oxadiazole (CAS 1376392-03-8)
- 9,10-Bis(2-(pyridin-4-yl)vinyl)anthracene (CAS 407626-74-8)
- Imazethapyr Impurity (Diethyl 5-ethylpyridine-2,3-dicarboxylate) (CAS 105151-39-1)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
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