3-methyl-1-[4-(trifluoromethyl)phenyl]hexahydropyrimidine-2,4-dione CAS 101394-18-7

Purity 97%+In StockPharmaceutical Standards
CAS No.101394-18-7
Molecular FormulaC12H11F3N2O2
Molecular Weight272.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-methyl-1-[4-(trifluoromethyl)phenyl]hexahydropyrimidine-2,4-dione CAS 101394-18-7 chemical structure

Description

As a certified reference material (CRM), 3-methyl-1-[4-(trifluoromethyl)phenyl]hexahydropyrimidine-2,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

CATO supplies 3-methyl-1-[4-(trifluoromethyl)phenyl]hexahydropyrimidine-2,4-dione (CAS 101394-18-7), a certified reference material (molecular formula C12H11F3N2O2, MW 272.22 g/mol) for analytical method development and quality control.

The molecular framework of 3-methyl-1-[4-(trifluoromethyl)phenyl]hexahydropyrimidine-2,4-dione (C12H11F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC12H11F3N2O2
Molecular Weight272.22 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF-containing
Nitrogen Atoms2

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