5-Phenyloxazole-2-carboxylic acid CAS 1014-14-8
| CAS No. | 1014-14-8 |
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Phenyloxazole-2-carboxylic acid.
5-Phenyloxazole-2-carboxylic acid (CAS 1014-14-8), molecular formula C10H7NO3 and molecular weight 189.17 g/mol, is a CATO reference standard with documented purity and traceability.
5-Phenyloxazole-2-carboxylic acid (C10H7NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Phenyloxazole-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Phenyloxazole Standards
- 2-Phenyloxazole-5-carboxylic acid (CAS 106833-79-8)
- 2-Phenyloxazole-4-carboxylic Acid (CAS 23012-16-0)
- 5-Phenyloxazole-4-carboxylic Acid (CAS 99924-18-2)
- 2-Methyl-4-phenyloxazole-5-carbaldehyde (CAS 1086379-16-9)
- 4-Methyl-2-phenyloxazole-5-carbaldehyde (CAS 953408-85-0)
- 4-methyl-2-phenyloxazole-5-carbonitrile (CAS 1404376-77-7)
- 4-Methyl-2-phenyloxazole-5-carboxamide (CAS 51655-70-0)
- Methyl 2-phenyloxazole-5-carboxylate (CAS 106833-83-4)
Recommended Standards
- 2-(Methoxycarbonylamino)-2-(oxetan-3-yl)acetic acid (CAS 1009120-05-1)
- 1-(Pyridin-2-yl)-1H-pyrazole-3-carboxylic acid (CAS 1014631-58-3)
- 2-Aminoquinazoline-4-carboxylic acid (CAS 100246-10-4)
- 1-(Pyridin-3-yl)-1H-pyrazole-3-carboxylic acid (CAS 1014631-62-9)
- Hexyl isooctyl phthalate Solution (CAS 71850-12-9)
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- Nabumetone Impurity 23 (CAS 56290-45-0)
- Anatalline (CAS 18793-19-6)
- pyrazolo[1,5-b]pyridazin-3-amine hydrochloride (CAS 136577-24-7)
- 3-Cyano-4,5-difluorobenzenesulfonyl chloride (CAS 1807047-95-5)
- Diethoxymethyl acetate (CAS 14036-06-7)
- 2-Chloro-4-methoxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 81532-47-0)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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