N-({1-[(4-Fluorophenyl)sulfonyl]piperidin-4-yl}carbonyl)-L-methionine CAS 1014412-10-2

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

N-({1-[(4-Fluorophenyl)sulfonyl]piperidin-4-yl}carbonyl)-L-methionine (CAS 1014412-10-2), molecular formula C17H23FN2O5S2 and molecular weight 418.50 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-({1-[(4-Fluorophenyl)sulfonyl]piperidin-4-yl}carbonyl)-L-methionine (C17H23FN2O5S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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