5-(Pyridin-3-yl)-1,3,4-thiadiazole-2-carboxylic acid CAS 1014630-04-6
| CAS No. | 1014630-04-6 |
| Molecular Formula | C8H5N3O2S |
| Molecular Weight | 207.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(Pyridin-3-yl)-1,3,4-thiadiazole-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-(Pyridin-3-yl)-1,3,4-thiadiazole-2-carboxylic acid (CAS 1014630-04-6) is a high-purity analytical reference standard with the molecular formula C8H5N3O2S and a molecular weight of 207.21 g/mol.
The molecular framework of 5-(Pyridin-3-yl)-1,3,4-thiadiazole-2-carboxylic acid (C8H5N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5N3O2S |
| Molecular Weight | 207.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pyridin Standards
- 5-(Pyridin-2-yl)-1,3,4-thiadiazole-2-carboxylic acid (CAS 1014629-99-2)
- 4-(Pyridin-3-yl)-1,2,3-thiadiazole-5-carboxylic acid (CAS 1083224-24-1)
- 4-(Pyridin-4-yl)-1,2,3-thiadiazole-5-carboxylic acid (CAS 1083401-67-5)
- 2-[(E)-(Pyridin-4-ylmethylidene)amino]benzonitrile (CAS 75273-74-4)
- 4-(Pyridin-4-yl)tetrahydro-2H-pyran-4-carboxylic acid (CAS 920297-31-0)
- 5-(Pyridin-3-yl)-1H-pyrazole-3-carbohydrazide (CAS 23424-35-3)
- (R)-1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)ethan-1-ol (CAS 1380649-51-3)
- 2-Methyl-5-((pyridin-3-ylmethyl)thio)-1,3,4-oxadiazole (CAS 604740-76-3)
Recommended Standards
- 2-(Pyrazin-2-yl)thiazole-5-carboxylic acid (CAS 1014630-94-4)
- Lead (CAS 7439-92-1)
- 2-(Pyrimidin-2-yl)-1,3-thiazole-5-carboxylic acid (CAS 1014630-98-8)
- N-(3,5-difluorophenyl)methanesulfonamide (CAS 358971-48-9)
- (S)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid--4-methylbenzenesulfonic acid (CAS 312623-76-0)
- 6-Chloro-N-cyclopropyl-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1206970-15-1)
- 4-(Difluoromethyl)cyclohexan-1-amine hydrochloride (CAS 1461709-26-1)
- 2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,4-diazepane-1-carbonyl}cyclopropane-1-carboxylic acid (CAS 1024151-62-9)
- 4-(2-(Ethylamino)propyl)phenol (CAS 69389-96-4)
- 1-Methyl-N-[4-(trifluoromethoxy)phenyl]-1-hydrazinecarbothioamide (CAS 1022545-32-9)
- 2-Hydroxyphenyl N-[(4-methylphenyl)methyl]sulfamate (CAS 478260-94-5)
- (2-Carboxy-1-phenylethyl)triphenylphosphonium bromide (CAS 29149-30-2)
- (S)-3-Aminopiperidin-2-One Hydrochloride (CAS 42538-31-8)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
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