Methyl 3-(phenylsulfonyl)propanoate CAS 10154-72-0
| CAS No. | 10154-72-0 |
| Molecular Formula | C10H12O4S |
| Molecular Weight | 228.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 3-(phenylsulfonyl)propanoate (C10H12O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Methyl 3-(phenylsulfonyl)propanoate (CAS 10154-72-0), a certified reference material (molecular formula C10H12O4S, MW 228.26 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12O4S |
| Molecular Weight | 228.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 2-Methyl-2-(phenylsulfonyl)propanoic acid (CAS 34220-23-0)
- 3-((Phenylsulfonyl)methyl)oxetan-3-ol (CAS 2306275-26-1)
- Ethyl 2-(phenylsulfonyl)acetate (CAS 7605-30-3)
- 2-(Phenylsulfonyl)propanehydrazide (CAS 886499-82-7)
- 5-(Phenylsulfonyl)pentan-1-amine (CAS 944325-14-8)
- 4-(Phenylsulfonyl)morpholine (CAS 5033-21-6)
- 2-[(phenylsulfonyl)amino]propanoic acid (CAS 42908-31-6)
- N-(Phenylsulfonyl)glycine Methyl Ester (CAS 69398-48-7)
Recommended Standards
- H-Gly-Pro-Gly-NH2 (CAS 141497-12-3)
- 3-(4-Methylbenzenesulfonyl)propanoic acid (CAS 10154-76-4)
- Tetraacetylethylenediamine (CAS 10543-57-4)
- 2-(Propane-1-sulfonyl)benzoic acid (CAS 1016687-98-1)
- 1-(2-Bromobenzyl)azetidine-3-carboxylic acid (CAS 1339510-66-5)
- (S)-tert-Butyl 1-(2-amino-6-fluorophenyl)pyrrolidin-3-ylcarbamate (CAS 1286207-29-1)
- N-(2,4-Difluorophenyl)-6-(1H-pyrazol-1-yl)pyridine-3-carboxamide (CAS 400078-68-4)
- 2,6-Dichloro-4-methoxyquinoline (CAS 952434-99-0)
- 1-(4-Chlorophenyl)-N-(3,4-dichlorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 861212-23-9)
- 1,3-Dimethyl 4,8-dioxoadamantane-1,3-dicarboxylate (CAS 64558-01-6)
- Boc-D-Pyroglutaminol (CAS 128811-37-0)
- tert-Butyl (3-amino-4,5-dimethylphenyl)carbamate (CAS 1936569-30-0)
- N-(3-Bromo-5-fluoropyridin-2-yl)acetamide (CAS 1065074-95-4)
- (Asp28)-Exenatide trifluoroacetate salt (CAS 1678417-24-7)
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