8-Chloro-6-iodoquinazolin-4(3H)-one CAS 101580-72-7
| CAS No. | 101580-72-7 |
| Molecular Formula | C8H4ClIN2O |
| Molecular Weight | 306.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
8-Chloro-6-iodoquinazolin-4(3H)-one (CAS 101580-72-7), molecular formula C8H4ClIN2O and molecular weight 306.49 g/mol, is a CATO reference standard with documented purity and traceability.
8-Chloro-6-iodoquinazolin-4(3H)-one (C8H4ClIN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 8-Chloro-6-iodoquinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4ClIN2O |
| Molecular Weight | 306.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-5-iodoquinazolin-4(3H)-one (CAS 1107694-74-5)
- 2-Chloro-8-iodoquinazolin-4(3H)-one (CAS 1107694-75-6)
- 5-Chloro-6-iodo-1h-pyrrolo[2,3-b]pyridine-4-carbaldehyde (CAS 1246088-64-1)
- 5-Chloro-3-iodo-7H-pyrrolo[2,3-b]pyridine-6-carbaldehyde (CAS 1346447-32-2)
- 6-Chloro-3-iodoimidazo-[1,2-a]pyridine-5-carbaldehyde (CAS 1414864-07-5)
- 7-CHloro-6-iodo-1h-quinazolin-4-one (CAS 1423187-59-0)
- 6-Chloro-3-iodocinnolin-4(1H)-one (CAS 1443292-33-8)
- 8-Chloro-3-iodo-1,7-naphthyridin-4(1H)-one (CAS 1812220-08-8)
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